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前列腺癌:兆伏级放射治疗的并发症

Prostatic carcinoma: complications of megavoltage radiation therapy.

作者信息

Lindholt J, Hansen P T

出版信息

Br J Urol. 1986 Feb;58(1):52-4. doi: 10.1111/j.1464-410x.1986.tb05427.x.

DOI:10.1111/j.1464-410x.1986.tb05427.x
PMID:3081075
Abstract

Megavoltage radiation therapy and radical prostatectomy are at present the only curative treatments for prostatic carcinoma. Because a high complication rate appeared to follow radiotherapy, all patients with prostatic carcinoma presenting to a Danish provincial hospital between 1975 and 1980 were reviewed. Of 31 radiation-treated patients, 23 had serious complications. No recurrence was noted in eight patients. Twenty-three had a recurrence despite radiotherapy but 11 of these patients had no local recurrence. In view of the high level of complications following radiation therapy and the high incidence of latent carcinomas in the prostate gland, a cautious approach to radiotherapy is recommended.

摘要

目前,兆伏级放射治疗和根治性前列腺切除术是前列腺癌仅有的治愈性治疗方法。由于放射治疗后似乎出现较高的并发症发生率,因此对1975年至1980年间到一家丹麦省级医院就诊的所有前列腺癌患者进行了回顾性研究。在31例接受放射治疗的患者中,23例出现严重并发症。8例患者未出现复发。23例患者尽管接受了放射治疗仍出现复发,但其中11例患者无局部复发。鉴于放射治疗后并发症发生率较高以及前列腺潜伏癌的高发病率,建议对放射治疗采取谨慎态度。

相似文献

1
Prostatic carcinoma: complications of megavoltage radiation therapy.前列腺癌:兆伏级放射治疗的并发症
Br J Urol. 1986 Feb;58(1):52-4. doi: 10.1111/j.1464-410x.1986.tb05427.x.
2
Postoperative irradiation in carcinoma of the prostate.前列腺癌的术后放疗
Int J Radiat Oncol Biol Phys. 1984 Oct;10(10):1869-73. doi: 10.1016/0360-3016(84)90264-5.
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Complications following external beam radiation therapy for prostate cancer: an analysis of patients treated with and without staging pelvic lymphadenectomy.前列腺癌外照射放疗后的并发症:对接受和未接受分期盆腔淋巴结清扫术治疗的患者的分析
J Urol. 1991 Sep;146(3):798-802. doi: 10.1016/s0022-5347(17)37924-7.
4
External-bean megavoltage radiation therapy in the treatment of post-radical prostatectomy residual or recurrent tumor preliminary results.体外兆伏级放射治疗根治性前列腺切除术后残留或复发性肿瘤的初步结果
J Urol. 1975 Jul;114(1):98-101. doi: 10.1016/s0022-5347(17)66953-2.
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Radiation enteritis following radiotherapy for prostatic carcinoma.前列腺癌放疗后的放射性肠炎。
Br J Urol. 1975 Aug;47(4):441-4. doi: 10.1111/j.1464-410x.1975.tb04003.x.
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[Vesicourethral anastomotic stricture following radical prostatectomy with or without postoperative radiotherapy].[根治性前列腺切除术后伴或不伴术后放疗的膀胱尿道吻合口狭窄]
Actas Urol Esp. 2011 May;35(5):277-81. doi: 10.1016/j.acuro.2011.01.003. Epub 2011 Mar 9.
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Radiation therapy in carcinoma of the prostate: a contributing cause of urinary incontinence.前列腺癌的放射治疗:尿失禁的一个促成因素。
J Urol. 1984 Nov;132(5):998-9. doi: 10.1016/s0022-5347(17)49985-x.
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Postoperative radiation therapy after radical prostatectomy for prostate carcinoma.前列腺癌根治性前列腺切除术后的术后放射治疗。
Cancer. 1992 Oct 1;70(7):1960-6. doi: 10.1002/1097-0142(19921001)70:7<1960::aid-cncr2820700725>3.0.co;2-w.
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Adjuvant radiotherapy following radical prostatectomy: results and complications.
J Urol. 1986 Jan;135(1):65-8. doi: 10.1016/s0022-5347(17)45519-4.
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Therapeutic options for localized carcinoma of the prostate: the role of external beam radiation therapy.前列腺局限性癌的治疗选择:外照射放疗的作用
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