Zemskov A M, Trutnev B D, Popova V P, Salomakhin G G, Dolzhanov A Ia, Mikstaĭs Iu Ia
Zh Mikrobiol Epidemiol Immunobiol. 1993 Sep-Oct(5):71-4.
The possibility of using sodium nucleinate for the treatment of acute dysentery has been confirmed in experiments on guinea pigs with the use of the keratoconjunctival test as an experimental model. The capacity of sodium nucleinate to enhance the antibiotic sensitivity of shigellae isolated from infected eyes to kanamycin, tetracycline and chloramphenicol has been established. The effect produced by individual ribonucleotides contained in sodium nucleinate have been studied and found to be differently directed.
以角膜结膜试验作为实验模型，在豚鼠身上进行的实验已证实了使用核酸钠治疗急性痢疾的可能性。已确定核酸钠能增强从感染眼部分离出的志贺氏菌对卡那霉素、四环素和氯霉素的抗生素敏感性。对核酸钠中所含个别核糖核苷酸产生的作用进行了研究，发现其作用方向不同。
