Levitt A J, Joffe R T, King E
Department of Psychiatry, University of Toronto, Ontario, Canada.
Acta Psychiatr Scand. 1994 May;89(5):341-5. doi: 10.1111/j.1600-0447.1994.tb01526.x.
Forty-three subjects with seasonal affective disorder were randomly assigned to receive 2 weeks of treatment with either bright- (mean 4106 lx) or dim-light (mean 96 lx) therapy, using red light-emitting diode light sources, in a head-mounted unit. Defining response as a 50% reduction in the 21-item Hamilton Depression Rating Scale score to a post-treatment score of less than 8, there was no significant difference in response rate between patients receiving bright light (67%) as compared with patients receiving dim light (68%). Possible explanations for the similar response rate to 2 very different illuminances of red light are discussed.
43名季节性情感障碍患者被随机分配，使用头戴式装置中的红色发光二极管光源，接受为期2周的强光（平均4106勒克斯）或弱光（平均96勒克斯）治疗。将反应定义为21项汉密尔顿抑郁量表评分降低50%，治疗后评分低于8分，接受强光治疗的患者（67%）与接受弱光治疗的患者（68%）的反应率没有显著差异。文中讨论了对两种光照强度差异极大的红光产生相似反应率的可能解释。
