Waller D A, Forty J, Morritt G N
Regional Cardiothoracic Centre, Freeman Hospital, Newcastle-upon-Tyne, United Kingdom.
Ann Thorac Surg. 1994 Aug;58(2):372-6; discussion 376-7. doi: 10.1016/0003-4975(94)92210-1.
In a prospective comparison, 60 patients suffering from complicated spontaneous pneumothorax were randomly allocated to receive treatment by a video-assisted thoracoscopic surgery (VATS) technique or by thoracotomy. Thirty patients underwent bullectomy and apical pleurectomy by VATS performed through three 2-cm incisions (group V) and 30 patients underwent a similar surgical procedure through a posterolateral thoracotomy (group T). The median operating time was significantly longer in group V (45 versus 37.5 minutes; p < 0.05), but the postoperative analgesic requirement and hospital stay were less than those in group T. On the third postoperative day, the reductions in the forced expiratory volume in 1 second and forced vital capacity were significantly lower in group V than in group T (p < 0.05 and p < 0.01, respectively). Initial treatment of the spontaneous pneumothorax was effective in 27 patients (90%) in group V and in 29 patients (97%) in group T. There have been two late recurrences in group V and one in group T at a median follow-up of 15.1 months and 16.3 months, respectively. Within the study group, 30 consecutive patients presented with primary spontaneous pneumothorax. In this subgroup there was no significant difference in the operating time between VATS and thoracotomy, but postoperative pain, hospital stay, and pulmonary dysfunction were all less for those undergoing VATS. All treatment failures were in the subgroup of 30 consecutive patients who presented with secondary spontaneous pneumothorax, and the hospital stay in this group was prolonged by the use of VATS. We conclude from our findings that VATS is superior to thoracotomy in the treatment of primary spontaneous pneumothorax.(ABSTRACT TRUNCATED AT 250 WORDS)
在一项前瞻性比较研究中,60例患有复杂性自发性气胸的患者被随机分配接受电视辅助胸腔镜手术(VATS)技术或开胸手术治疗。30例患者通过三个2厘米的切口经VATS进行肺大疱切除术和胸膜顶切除术(V组),30例患者通过后外侧开胸进行类似的手术操作(T组)。V组的中位手术时间明显更长(45分钟对37.5分钟;p<0.05),但术后镇痛需求和住院时间比T组少。术后第三天,V组一秒用力呼气量和用力肺活量的下降明显低于T组(分别为p<0.05和p<0.01)。V组27例患者(90%)和T组29例患者(97%)的自发性气胸初始治疗有效。V组有2例晚期复发,T组有1例晚期复发,中位随访时间分别为15.1个月和16.3个月。在研究组中,30例连续患者表现为原发性自发性气胸。在这个亚组中,VATS和开胸手术的手术时间没有显著差异,但接受VATS的患者术后疼痛、住院时间和肺功能障碍都更少。所有治疗失败均发生在30例连续表现为继发性自发性气胸的患者亚组中,该组使用VATS后住院时间延长。我们从研究结果中得出结论,在原发性自发性气胸的治疗中,VATS优于开胸手术。(摘要截断于250字)