Guest C S, O'Dea K, Larkins R G
Department of Medicine (Royal Melbourne Hospital), University of Melbourne, South Australia.
Aust J Public Health. 1994 Mar;18(1):79-86. doi: 10.1111/j.1753-6405.1994.tb00200.x.
Based on a survey in two country towns of southeastern Australia, cardiovascular risk-factor prevalence data from Aborigines and persons of European descent are presented. The mean diastolic blood pressure in 123 Aboriginal males was 83.2 mmHg, compared with 79.2 mmHg in 272 European males (P = 0.005). In 178 Aboriginal females, mean diastolic pressure was 79.2 mmHg, compared with 76.3 mmHg in 281 European females (P = 0.006). Mean plasma total cholesterol was higher in Europeans (both males and females: 5.7 mmol/L) than in Aborigines (in males 5.2 and females 5.0 mmol/L) (male comparison, P = 0.02, female comparison, P < 0.001). The prevalence in participants aged 25 to 64 years of at least one major risk factor (diastolic blood pressure 95 mmHg or higher, plasma cholesterol 6.5 mmol/L or higher, or smoking more than one cigarette daily) was higher in both these samples of Aborigines (94 per cent in males, 89 per cent in females) and Europeans (70 per cent in males, 59 per cent in females) than in the 1989 urban sample of the National Heart Foundation (47 per cent in males, 36 per cent in females). Multivariate analyses showed statistically significant independent contributions of body mass index and the variable 'ethnicity' (unidentified genetic and environmental differences between the groups) to blood pressure and other risk factors. The higher cardiovascular mortality of Aborigines may be explained partly by the higher prevalence of risk factors in this group compared with other Australians. Further, the risk-factor profile may be worse among rural compared with urban Europeans.
基于对澳大利亚东南部两个乡村小镇的一项调查,给出了原住民和欧洲裔人群心血管危险因素患病率数据。123名原住民男性的平均舒张压为83.2毫米汞柱,而272名欧洲裔男性为79.2毫米汞柱(P = 0.005)。178名原住民女性的平均舒张压为79.2毫米汞柱,281名欧洲裔女性为76.3毫米汞柱(P = 0.006)。欧洲人(男性和女性:5.7毫摩尔/升)的血浆总胆固醇平均水平高于原住民(男性5.2毫摩尔/升,女性5.0毫摩尔/升)(男性比较,P = 0.02,女性比较,P < 0.001)。在25至64岁的参与者中,至少有一种主要危险因素(舒张压95毫米汞柱或更高、血浆胆固醇6.5毫摩尔/升或更高、或每天吸烟超过一支)的患病率,在这两个原住民样本(男性94%,女性89%)和欧洲裔样本(男性70%,女性59%)中均高于1989年国家心脏基金会的城市样本(男性47%,女性36%)。多变量分析显示,体重指数和“种族”变量(两组间未明确的遗传和环境差异)对血压及其他危险因素有统计学上显著的独立影响。与其他澳大利亚人相比,原住民较高的心血管死亡率可能部分归因于该群体中危险因素的患病率较高。此外,农村欧洲裔人群的危险因素状况可能比城市欧洲裔人群更差。