Tigner J C, Barnes R H
Proc Soc Exp Biol Med. 1975 May;149(1):80-2. doi: 10.3181/00379727-149-38747.
Basal morning plasma corticosteroid concentrations were significantly elevated in 11 and 21 day old male albino rats suckled by dams receiving a 12% casein diet when compared to control rats suckled by dams receiving a 25% casein diet. Rats which were either well-fed or malnourished during lactation then given a 9% casein after weaning had elevated corticosteroid levels and adrenal hypertrophy at 49 days of age. These changes may be related to altered adrenocortical responsivity found in adult rats malnourished in infancy.
与由食用25%酪蛋白饮食的母鼠哺育的对照大鼠相比，由食用12%酪蛋白饮食的母鼠哺育的11日龄和21日龄雄性白化大鼠的基础晨间血浆皮质类固醇浓度显著升高。在哺乳期要么营养良好要么营养不良、断奶后给予9%酪蛋白饮食的大鼠，在49日龄时皮质类固醇水平升高且肾上腺肥大。这些变化可能与婴儿期营养不良的成年大鼠中发现的肾上腺皮质反应性改变有关。
