Druzin M L, Stier E
Department of Obstetrics and Gynecology, New York Hospital, Cornell Medical Center, New York.
J Am Coll Surg. 1994 Sep;179(3):264-6.
The relationship between maternal platelet count at the time of cesarean section and perioperative and postpartum operative complications was examined.
A retrospective analysis of 46 pregnancies in 41 women with histories of idiopathic thrombocytopenic purpura was performed. Thirty-five patients had platelet counts greater than 100,000 before delivery and 11 had counts less than 100,000. Statistical comparisons were made using Student's t test and chi-square test.
The perioperative and postpartum course for patients in the two groups differed significantly only in platelet counts at delivery. Change in hematocrit (from admission to postpartum), estimated blood loss at cesarean section, incidence of wound complications or transfusion, were not significantly different. There were no neonatal complications.
Mild thrombocytopenia in patients with idiopathic thrombocytopenic purpura is unlikely to be associated with an increase in blood loss, infection, wound complication, or need for transfusion.
研究剖宫产时产妇血小板计数与围手术期及产后手术并发症之间的关系。
对41例有特发性血小板减少性紫癜病史的女性的46次妊娠进行回顾性分析。35例患者分娩前血小板计数大于100,000,11例患者血小板计数小于100,000。采用学生t检验和卡方检验进行统计学比较。
两组患者围手术期及产后过程仅在分娩时血小板计数上有显著差异。血细胞比容变化(从入院到产后)、剖宫产估计失血量、伤口并发症或输血发生率无显著差异。无新生儿并发症。
特发性血小板减少性紫癜患者的轻度血小板减少不太可能与失血量增加、感染、伤口并发症或输血需求增加有关。