Bongianni F, Mutolo D, Srinivasan M, Staderini G, Baccari M C, Calamai F, Pantaleo T
Dipartimento di Scienze Fisiologiche, Università di Firenze, Florence, Italy.
Brain Res. 1994 May 23;646(2):307-11. doi: 10.1016/0006-8993(94)90095-7.
Microinjections of DL-homocysteic acid into the area postrema (AP) of anesthetized rabbits provoked gastric relaxations associated with small changes in blood pressure and marked excitatory effects on respiration. Both gastric and cardiovascular effects failed to occur after bilateral vagotomy. Comparable gastric relaxations were induced before and after treatment with atropine or atropine and guanethidine. The AP appears to play a role in gastric motility via vagus nerves and nonadrenergic noncholinergic intramural inhibitory neurons.
向麻醉兔的最后区（AP）微量注射DL-高胱氨酸可引起胃舒张，同时伴有血压的微小变化以及对呼吸的显著兴奋作用。双侧迷走神经切断术后，胃和心血管效应均未出现。阿托品或阿托品与胍乙啶治疗前后均可诱导出类似的胃舒张。最后区似乎通过迷走神经和非肾上腺素能非胆碱能壁内抑制性神经元对胃运动起作用。
