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犊牛实验性诱导的肉孢子虫感染:病理学

Experimentally induced sarcocystis infection in calves: pathology.

作者信息

Johnson A J, Hildebrandt P K, Fayer R

出版信息

Am J Vet Res. 1975 Jul;36(7):995-9.

PMID:807136
Abstract

Calves fed sporocysts of Sarcocystis isolated from the feces of dogs and coyotes became anorectic, lost weight, and became anemic and prostrate, and died. The most severe pathologic changes occurred between 26 and 33 days after infection; schizonts were found throughout the body. Schizonts were not found after this time. Sarcocytis cysts were in skeletal and cardiac muscles between 33 and 54 days. Necropsy revealed lymphadenopathy, paleness of the mucous membranes and visceral organs, ascites, hydrothorax, hydropericardium, and serous atrophy of fat. Ecchymotic or petechial hemorrhage was in heart, brain, serosa of the alimentary tract, and urinary bladder. Microscopic changes observed in nearly all calves consisted of hemorrhage, mononuclear cell (primarily lymphocytic) infiltration and edema in heart, brain, liver, lung, kidney, and striated muscle. Necrotizing myocarditis with dystrophic calcification of the striated muscle and fat, as well as nonsuppurative inflammation of meninges and glial nodules in the brain, was observed in several calves.

摘要

用从狗和郊狼粪便中分离出的肉孢子虫孢子囊喂养的小牛出现食欲不振、体重减轻、贫血并变得虚弱,最终死亡。最严重的病理变化发生在感染后26至33天之间;全身发现裂殖体。在此之后未发现裂殖体。在33至54天之间,骨骼肌和心肌中出现肉孢子虫囊肿。尸检显示淋巴结病、粘膜和内脏器官苍白、腹水、胸腔积液、心包积液以及脂肪的浆液性萎缩。心脏、大脑、消化道浆膜和膀胱出现瘀斑或瘀点出血。几乎所有小牛观察到的微观变化包括心脏、大脑、肝脏、肺、肾脏和横纹肌中的出血、单核细胞(主要是淋巴细胞)浸润和水肿。在几只小牛中观察到坏死性心肌炎伴横纹肌和脂肪的营养不良性钙化,以及大脑中的脑膜非化脓性炎症和神经胶质结节。

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Experimentally induced sarcocystis infection in calves: pathology.犊牛实验性诱导的肉孢子虫感染:病理学
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Quantitative parasitemia in calves fed Sarcocystis cruzi sporocysts from coyotes.用来自郊狼的克氏肉孢子虫孢子囊喂养的犊牛的定量寄生虫血症。
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