Hedican S P, Walsh P C
James Buchanan Brady Urological Institute, Johns Hopkins Medical Institutions, Baltimore, Maryland.
J Urol. 1994 Oct;152(4):1181-3. doi: 10.1016/s0022-5347(17)32534-x.
Bleeding following radical prostatectomy is defined as significant postoperative hemorrhage requiring the acute transfusion of blood to support blood pressure. Of 1,350 consecutive radical prostatectomies 7 cases (0.5%) met this criterion. Of these patients 4 were explored for bleeding and 3 were managed expectantly. Mean blood product requirements for explored patients were comparable to those managed conservatively (13.8 versus 14.7). Total hospitalization days were less in patients who underwent a secondary operation (14.5 versus 21 days). In the 3 patients managed nonoperatively the pelvic hematoma drained through the anastomosis, resulting in symptomatic bladder neck contractures in all 3 and long-term incontinence in 2. Only 1 of the 4 patients explored (25%) experienced prolonged mild incontinence. These results suggest that patients requiring acute transfusions for hypotension following radical prostatectomy should be explored to evacuate the pelvic hematoma, and decrease the likelihood of bladder neck contracture and incontinence.
根治性前列腺切除术后出血被定义为术后严重出血,需要紧急输血以维持血压。在连续1350例根治性前列腺切除术中,有7例(0.5%)符合该标准。这些患者中,4例因出血接受了探查,3例采取了保守治疗。接受探查的患者的平均血液制品需求量与保守治疗的患者相当(分别为13.8和14.7)。接受二次手术的患者的总住院天数较少(分别为14.5天和21天)。在3例非手术治疗的患者中,盆腔血肿通过吻合口引流,导致所有3例患者出现有症状的膀胱颈挛缩,2例患者出现长期尿失禁。4例接受探查的患者中只有1例(25%)出现了持续的轻度尿失禁。这些结果表明,根治性前列腺切除术后因低血压需要紧急输血的患者应接受探查以清除盆腔血肿,并降低膀胱颈挛缩和尿失禁的可能性。