副蛋白血症中的免疫紊乱
immunoperturbation in paraproteinemia.
作者信息
Barandum S, Morell A, Skvaril F, Keller H
出版信息
Birth Defects Orig Artic Ser. 1975;11(1):95-8.
PMID:807276
Abstract
The immunoperturbations in paraproteinemias are due predominantly to a disturbance of the B-cell system. The immunologic deficiency is characterized clinically by an increased susceptibility to infections and serologically by a reduction of the nonmyeloma immunoglobulins. In advances cases the capacity to produce specific antibodies is impaired. This may be attributed to a low rate of synthesis or an increased catabolism of normal immunoglobulins.
摘要
副蛋白血症中的免疫紊乱主要是由于B细胞系统的紊乱所致。免疫缺陷在临床上表现为对感染的易感性增加，在血清学上表现为非骨髓瘤免疫球蛋白减少。在病情进展的病例中，产生特异性抗体的能力受损。这可能归因于正常免疫球蛋白的合成率低或分解代谢增加。
相似文献
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immunoperturbation in paraproteinemia.副蛋白血症中的免疫紊乱
Birth Defects Orig Artic Ser. 1975;11(1):95-8.
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