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使用免疫过氧化物酶技术对多发性骨髓瘤及相关病症的福尔马林 - 石蜡切片中的细胞内免疫球蛋白进行免疫组织学检测。

The immunohistological detection of intracellular immunoglobulin in formalin-paraffin sections from multiple myeloma and related conditions using the immunoperoxidase technique.

作者信息

Taylor C R, Mason D Y

出版信息

Clin Exp Immunol. 1974 Nov;18(3):417-29.

PMID:4219910
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1537991/
Abstract

Paraffin sections of tissues from thirty-three cases of plasma cell neoplasia have been examined by an immunoperoxidase method for demonstrating and characterizing intracellular immunoglobulins. The specificity of the method has been confirmed by a comparison of results with the serum paraprotein types analysed independently. The morphology of some of the immunoglobulin-containing cells is discussed and possible diagnostic applications of the method are briefly described.

摘要

采用免疫过氧化物酶法对33例浆细胞肿瘤组织的石蜡切片进行检查，以显示和鉴定细胞内免疫球蛋白。通过将结果与独立分析的血清副蛋白类型进行比较，证实了该方法的特异性。讨论了一些含免疫球蛋白细胞的形态，并简要描述了该方法可能的诊断应用。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/cdb0/1537991/c6b28026f5b7/clinexpimmunol00268-0129-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/cdb0/1537991/8ea8fe877280/clinexpimmunol00268-0125-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/cdb0/1537991/0d0b0e632e94/clinexpimmunol00268-0126-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/cdb0/1537991/96af6e9111d5/clinexpimmunol00268-0127-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/cdb0/1537991/c28306159a94/clinexpimmunol00268-0128-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/cdb0/1537991/c6b28026f5b7/clinexpimmunol00268-0129-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/cdb0/1537991/8ea8fe877280/clinexpimmunol00268-0125-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/cdb0/1537991/0d0b0e632e94/clinexpimmunol00268-0126-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/cdb0/1537991/96af6e9111d5/clinexpimmunol00268-0127-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/cdb0/1537991/c28306159a94/clinexpimmunol00268-0128-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/cdb0/1537991/c6b28026f5b7/clinexpimmunol00268-0129-a.jpg

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Ann Intern Med. 1965 May;62:1025-45. doi: 10.7326/0003-4819-62-5-1025.
2
[Method permitting the combined study of the electrophoretic and the immunochemical properties of protein mixtures; application to blood serum].[蛋白质混合物电泳和免疫化学性质联合研究方法；应用于血清]
Biochim Biophys Acta. 1953 Jan;10(1):193-4. doi: 10.1016/0006-3002(53)90233-9.
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The early stages of absorption of injected horseradish peroxidase in the proximal tubules of mouse kidney: ultrastructural cytochemistry by a new technique.
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Methods Mol Biol. 2021;2366:27-42. doi: 10.1007/978-1-0716-1669-7_3.
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Antigen retrieval immunohistochemistry: review and future prospects in research and diagnosis over two decades.抗原修复免疫组化：二十多年来在研究和诊断中的回顾与展望。
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