[Dynamics of various parameters of intraosseous pressure in acute disorders of regional blood flow in an experiment].

The authors studied the time course in changes of the physiological indices and regularities of the restoration of intraosseous pressure (IOP) parameters after acute disturbance of the blood flow in arteries and veins of the bone and extremity in experiments. The static parameters characterizing the intraosseous circulation were determined. It was established that short-term blood flow disorders lead to regular shifts of the IOP level which are compensated by the inflow of blood from collateral channels; stable disorders of the blood flow--embolization of the diaphyseal artery--lead to the formation of an extensive zone of excluded microcirculation due to cellular block of the sinusoidal bed and end in ischemic necrosis of the bone marrow.