Loewenson P R, White K E, Osterholm M T, MacDonald K L
Acute Disease Epidemiology Section, Minnesota Department of Health, Minneapolis 55440-9441.
Pediatr Infect Dis J. 1994 May;13(5):373-8. doi: 10.1097/00006454-199405000-00008.
Physician attitudes and practices regarding universal infant vaccination against hepatitis B virus infection in Minnesota were assessed approximately 1 year after publication of the Immunization Practices Advisory Committee recommendations. Four-hundred eighteen Minnesota family physicians and pediatricians were sent self-administered questionnaires, with follow-up by telephone. Among physicians who provide care to infants, 67 (29%) of 234 family physicians and 29 (50%) of 58 pediatricians routinely offered hepatitis B vaccine to all infants (overall 33%) (P = 0.002). The recommendations of the Immunization Practices Advisory Committee, the American Academy of Pediatrics and the American Academy of Family Physicians had the greatest positive influence on physicians' opinions regarding routine hepatitis B vaccination. The factors with the greatest negative influence on their opinions were the low prevalence of hepatitis B virus infection in Minnesota and the addition of three injections to the current childhood immunization schedule. Universal infant hepatitis B vaccination remains controversial among Minnesota family physicians and pediatricians. We believe, given the variability in hepatitis B virus incidence and prevalence in the United States and the relatively low risk of most infants, that a single national policy based solely on universal infant immunization may be difficult to implement.
在免疫实践咨询委员会发布相关建议约一年后,对明尼苏达州医生关于普遍为婴儿接种乙肝病毒感染疫苗的态度和做法进行了评估。向418名明尼苏达州的家庭医生和儿科医生发送了自填式问卷,并通过电话进行随访。在为婴儿提供护理的医生中,234名家庭医生中有67名(29%)、58名儿科医生中有29名(50%)会常规为所有婴儿提供乙肝疫苗(总体为33%)(P = 0.002)。免疫实践咨询委员会、美国儿科学会和美国家庭医生学会的建议对医生关于常规乙肝疫苗接种的意见产生了最大的积极影响。对他们的意见产生最大负面影响的因素是明尼苏达州乙肝病毒感染的低流行率以及在当前儿童免疫接种计划中增加了三针接种。普遍为婴儿接种乙肝疫苗在明尼苏达州的家庭医生和儿科医生中仍然存在争议。我们认为,鉴于美国乙肝病毒发病率和流行率的差异以及大多数婴儿相对较低的风险,仅基于普遍为婴儿免疫的单一国家政策可能难以实施。