Hirohashi S, Hirohashi R, Uchida H, Kitano S, Tanaka M, Matsuo N, Ohishi H
Department of Radiology, Nara Medical University.
Nihon Igaku Hoshasen Gakkai Zasshi. 1994 Jul 25;54(8):784-8.
To investigate the usefulness of MRI oral contrast media in enhancing the entire small intestine using FerriSeltz (Otsuka Pharmaceuticals, Tokyo), which contains ferric ammonium citrate, we compared the relaxation times and taste of 7 kinds of contrast media (Milk FerriSeltz A-G) that contain FerriSeltz dissolved in 7 different ratios of distilled water-milk. We also compared the homogeneity of the contrast enhancement of the entire small intestine on T1-weighted images between Milk FerriSeltz-F (a mixture of distilled water and milk at a ratio of 1:5 with FerriSeltz), which was found to be the best contrast medium based on the relaxation times and taste, and Milk FerriSeltz-A (distilled water with FerriSeltz) in 10 healthy volunteers. The T1 and T2 values decreased as the proportion of milk increased. The T1 and T2 values of Milk FerriSeltz-F were 71 msec and 28 msec, markedly shorter than those of Milk FerriSeltz-A (340 msec and 290 msec). T1-weighted images taken with Milk FerriSeltz-F showed more homogeneous enhancement of the entire small intestine than those taken with Milk FerriSeltz-A. There were no adverse effects in these 10 volunteers. Milk FerriSeltz-F seems to be an ideal oral contrast medium for enhancement of the entire small intestine.
为了研究使用含有柠檬酸铁铵的FerriSeltz（大冢制药，东京）作为MRI口服造影剂增强整个小肠的效果，我们比较了7种造影剂（FerriSeltz牛奶A - G）的弛豫时间和口感，这些造影剂是将FerriSeltz溶解在7种不同比例的蒸馏水 - 牛奶中制成的。我们还在10名健康志愿者中比较了基于弛豫时间和口感被认为是最佳造影剂的FerriSeltz牛奶 - F（蒸馏水与牛奶以1:5比例混合并含有FerriSeltz）和FerriSeltz牛奶 - A（含FerriSeltz的蒸馏水）在T1加权图像上整个小肠造影增强的均匀性。随着牛奶比例的增加，T1和T2值降低。FerriSeltz牛奶 - F的T1和T2值分别为71毫秒和28毫秒，明显短于FerriSeltz牛奶 - A的（340毫秒和290毫秒）。用FerriSeltz牛奶 - F拍摄的T1加权图像显示整个小肠的增强比用FerriSeltz牛奶 - A拍摄的更均匀。这10名志愿者均未出现不良反应。FerriSeltz牛奶 - F似乎是增强整个小肠的理想口服造影剂。
