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Isolation of a polysaccharide with antiviral effect from Ulva lactuca.

作者信息

Ivanova V, Rouseva R, Kolarova M, Serkedjieva J, Rachev R, Manolova N

机构信息

Institute of Microbiology, Bulgarian Academy of Science, Sofia.

出版信息

Prep Biochem. 1994 May;24(2):83-97. doi: 10.1080/10826069408010084.

DOI:10.1080/10826069408010084
PMID:8072958
Abstract

A polysaccharide from the green marine algae Ulva lactuca has been isolated. The substance has been investigated after acid hydrolysis by thin-layer and gas chromatography. The following carbohydrate components have been found: arabinose-xylose-rhamnose-galactose-mannose-glucose in ratio 1:1:9:5:2.5:16 respectively. One unidentified sugar has been demonstrated too. The polysaccharide has been studied for antiviral activity in vitro against a number of human and avian influenza viruses. A considerable inhibition of the viral reproduction was found. The effect was dose-dependent, strain-specific and selective.

摘要

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