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输血中统计方法的准确性:对1992年7/8月至1993年6月文章的综述

Accuracy of statistical methods in TRANSFUSION: a review of articles from July/August 1992 through June 1993.

作者信息

Kanter M H, Taylor J R

机构信息

Department of Pathology, Kaiser Permanente Medical Care Program, Los Angeles, California.

出版信息

Transfusion. 1994 Aug;34(8):697-701. doi: 10.1046/j.1537-2995.1994.34894353466.x.

DOI:10.1046/j.1537-2995.1994.34894353466.x
PMID:8073487
Abstract

BACKGROUND

Statistical errors have been noted in a large percentage of articles appearing in medical journals. Their incidence in a blood banking journal, however, has not been studied.

STUDY DESIGN AND METHODS

Original articles appearing in the journal TRANSFUSION from July 1992 through June 1993 were analyzed for correctness of statistical methods. Each article was reviewed by both a transfusion medicine physician and a statistician.

RESULTS

There were 122 original articles, of which 59 contained statistical methods and were reviewed. Of these, 23 (39%) contained an error in the statistical description of their data, 47 (80%) failed to describe clearly the statistical tests performed, and 44 (75%) involved an incorrect statistical test or contained an error in test calculation or interpretation. As a result of these errors, 13 (22%) of the 55 articles analyzed reported conclusions not supported by the data.

CONCLUSION

Misuse of statistical methodology may not be uncommon in transfusion medicine research, and it would be prudent to give more attention to statistical methodology in such research.

摘要

背景

医学期刊上发表的文章中,很大一部分都存在统计错误。然而,输血医学期刊中此类错误的发生率尚未得到研究。

研究设计与方法

对1992年7月至1993年6月发表在《输血》杂志上的原创文章进行统计方法正确性分析。每篇文章均由一位输血医学医生和一位统计学家进行审阅。

结果

共有122篇原创文章,其中59篇包含统计方法并接受了审阅。在这些文章中,23篇(39%)在数据的统计描述上存在错误,47篇(80%)未能清晰描述所进行的统计检验,44篇(75%)涉及错误的统计检验,或在检验计算或解释上存在错误。由于这些错误,在分析的55篇文章中,有13篇(22%)报告的结论未得到数据支持。

结论

统计方法的误用在输血医学研究中可能并不罕见,在这类研究中更加关注统计方法是审慎之举。

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