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[骨髓捐献者中央登记处及非血缘供者骨髓移植项目——20个月的经验]

[The central registry of bone marrow donors and the program for bone marrow transplantation from unrelated donors--20 months' experience].

作者信息

Koza V, Bártová A, Herynková R, Svojgrová M, Pittrová H

机构信息

I. interní klinika FN Plzen.

出版信息

Vnitr Lek. 1994 Jul;40(7):416-9.

PMID:8073656
Abstract

The authors describe their 20 months' experience with the establishment of a bone marrow register in the Czech Republic and its practical association with the programme of bone marrow transplantations from non-related subjects. During the 20 months of activity 5455 voluntary bone marrow donors were examined and at present more than 500 new voluntary donors are examined every month. For 21 patients a HLA identical unrelated donor is sought. For four patients a HLA compatible donor was found. The first bone marrow transplantation from a unrelated donor was performed and another patient is prepared for transplantation within the next few days. The authors discuss professional, organizational, moral and ethical problems associated with the elaboration of this medical programme.

摘要

作者描述了他们在捷克共和国建立骨髓登记处及其与非亲属骨髓移植项目实际关联方面的20个月经验。在20个月的活动期间,对5455名自愿骨髓捐献者进行了检查,目前每月有超过500名新的自愿捐献者接受检查。为21名患者寻找HLA配型相同的非亲属捐献者。为4名患者找到了HLA配型相合的捐献者。实施了首例非亲属捐献者的骨髓移植,另一名患者在未来几天内准备接受移植。作者讨论了与制定该医疗项目相关的专业、组织、道德和伦理问题。

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