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[血管加压素刺激兔肾髓袢升支中腺苷酸环化酶的活性]

[Vasopressin-stimulated adenyl cyclase activity in the ascending portions of rabbit kidney nephron loops].

作者信息

Imbert M, Chabardes D, Montegut M, Clique A, Morel F

出版信息

C R Acad Hebd Seances Acad Sci D. 1975 May 12;280(18):2129-32.

PMID:807399
Abstract

The adenylate-cyclase activity contained in the successive segments of the loop of Henle was measured using single tubular pieces isolated by microdissection. Vasopressin (10 (-6) M) had no significant effect on either the pars recta or the thin descending limb; whereas, it stimulated the enzyme contained in the thin ascending limb (8.9 fold as a mean value) and that contained in the medullary portion of the large ascending limb (14.7 fold).

摘要

采用显微解剖分离出的单个肾小管节段,测定了髓袢连续节段中所含的腺苷酸环化酶活性。血管加压素(10^(-6) M)对直部或细降支均无显著影响;然而,它刺激了细升支中所含的酶(平均值为8.9倍)以及大升支髓质部分中所含的酶(14.7倍)。

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