Schuster J J, Phillips C D, Levine P A
Department of Radiology, University of Virginia Health Sciences Center, Charlottesville 22908.
AJNR Am J Neuroradiol. 1994 Jun;15(6):1169-77.
To analyze the MR characteristics of a series of patients with esthesioneuroblastoma and discuss the typical surgery and its postoperative MR appearance.
The MR studies of 15 patients with the pathologic diagnosis of esthesioneuroblastoma (also known as olfactory neuroblastoma) were retrospectively reviewed and correlated with CT and surgical findings. The postoperative MR studies of 10 patients who underwent craniofacial resection were also reviewed.
In all cases the tumors arose in the superior nasal cavity and extended into the ethmoid cells. In some instances the tumors extended into the other paranasal sinuses, orbits, anterior cranial fossa, and cavernous sinus. The tumors were typically expansile and destructive in their growth patterns. Compared with brain gray matter, the tumors were hypointense on T1-weighted images and isointense to hyperintense on T2-weighted images. Nine tumors were heterogeneous and 6 were homogeneous. Contrast enhancement ranged from mild to marked. MR was useful for characterizing the various tissues and distinguishing fluid in the postoperative nasal cavity.
Esthesioneuroblastoma, although an uncommon tumor, may be suspected in lesions of the superior nasal cavity demonstrating both expansile and destructive growth properties. The MR findings are otherwise nonspecific. MR is the imaging modality of choice for depicting local tumor extension and evaluating for recurrence after craniofacial resection.
分析一系列嗅神经母细胞瘤患者的磁共振成像（MR）特征，并探讨典型手术方式及其术后MR表现。
回顾性分析15例经病理诊断为嗅神经母细胞瘤（又称嗅觉神经母细胞瘤）患者的MR检查结果，并与CT及手术所见进行对照。同时回顾了10例行颅面切除术患者的术后MR检查结果。
所有病例中肿瘤均起源于鼻腔上部并延伸至筛窦。部分病例中肿瘤还延伸至其他鼻窦、眼眶、前颅窝及海绵窦。肿瘤生长方式多为膨胀性及浸润性。与脑灰质相比，肿瘤在T1加权像上呈低信号，在T2加权像上呈等信号至高信号。9例肿瘤信号不均匀，6例均匀。增强扫描强化程度从轻度到明显不等。MR有助于区分术后鼻腔内的各种组织及液体。
嗅神经母细胞瘤虽为罕见肿瘤，但对于鼻腔上部具有膨胀性及浸润性生长特征的病变应考虑本病。MR表现无特异性。MR是显示肿瘤局部侵犯及评估颅面切除术后复发情况的首选影像学检查方法。
