Li C, Yousem D M, Hayden R E, Doty R L
Department of Otorhinolaryngology and Head and Neck Surgery, Hospital of the University of Pennsylvania, Philadelphia 19104.
AJNR Am J Neuroradiol. 1993 Sep-Oct;14(5):1167-71.
To evaluate MR in the diagnosis and staging of olfactory neuroblastoma.
Five patients with histologically proved olfactory neuroblastomas were studied by MR. Four also had CT scans.
The extent of disease delineated by MR agreed with surgical findings and surgical staging of the tumor in all five patients. All cases of olfactory neuroblastomas originated in the nasal cavity and involved the ethmoid sinuses. In three of the five cases, the tumors extended to the anterior skull base. In one case MR correctly suggested skull base involvement missed on CT. Lesions were isointense to hyperintense with muscle on T1-weighted scans. Compared with fat on T2-weighted scans, olfactory neuroblastomas were variable in signal intensity. Enhancement was minimal to moderate in all cases.
In the evaluation of olfactory neuroblastoma, MR is most useful in delineating the extent of the tumor and may be more accurate than CT. However, the signal intensity characteristics of olfactory neuroblastomas may overlap other tumors.
评估磁共振成像（MR）在嗅神经母细胞瘤诊断及分期中的作用。
对5例经组织学证实的嗅神经母细胞瘤患者进行了MR检查。其中4例还进行了CT扫描。
MR所显示的病变范围与所有5例患者的手术结果及肿瘤手术分期相符。所有嗅神经母细胞瘤病例均起源于鼻腔并累及筛窦。5例中有3例肿瘤延伸至前颅底。1例中MR正确提示了CT漏诊的颅底受累情况。在T1加权扫描上，病变与肌肉等信号或高信号。在T2加权扫描上，与脂肪相比，嗅神经母细胞瘤信号强度各异。所有病例强化程度均为轻度至中度。
在评估嗅神经母细胞瘤时，MR在描绘肿瘤范围方面最有用，且可能比CT更准确。然而，嗅神经母细胞瘤的信号强度特征可能与其他肿瘤重叠。
