Mentec H, Chosidow O, Lafaurie P, Darmon J Y, Simon M, Roujeau J C, Brun-Buisson C H
Service de Réanimation médicale, Hôpital Henri-Mondor, Créteil.
Ann Dermatol Venereol. 1993;120(12):889-91.
Necrotizing fasciitis is usually due to Streptococcus species but can be caused by a variety of organisms, among which Neisseria species are distinctly rare, as only four cases have been reported in the literature.
We report the first case of Neisseria meningitidis necrotizing fasciitis in a non-immunocompromised man, with a possibly predisposing effect of non-steroidal anti-inflammatory drugs. Neisseria meningitidis group C was isolated from subcutaneous and bullae aspirates. The involvement of two distant sites strongly suggests hematogenous dissemination of the microorganism. Four previous cases of fasciitis caused by Neisseria species are reviewed.
Although Streptococcus group A is the main cause of apparently primary necrotizing fasciitis, Neisseria meningitidis must be considered a possible etiologic agent of this severe soft tissue infection.
坏死性筋膜炎通常由链球菌属引起，但也可由多种微生物导致，其中奈瑟菌属极为罕见，文献中仅报道过4例。
我们报告了首例非免疫功能低下男性患脑膜炎奈瑟菌坏死性筋膜炎的病例，非甾体抗炎药可能起到了诱发作用。从皮下和水疱抽吸物中分离出C群脑膜炎奈瑟菌。两个相距较远部位的受累强烈提示该微生物发生了血行播散。回顾了之前4例由奈瑟菌属引起的筋膜炎病例。
虽然A组链球菌是明显原发性坏死性筋膜炎的主要病因，但脑膜炎奈瑟菌必须被视为这种严重软组织感染的一种可能病原体。
