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一名持续性非卧床腹膜透析患者发生脑膜炎奈瑟菌腹膜炎:首例病例报告及文献复习

Neisseria meningitidis peritonitis in a CAPD patient: first case report and review of the literature.

作者信息

Kleinpeter M A, Krane N K

机构信息

Tulane University School of Medicine, Department of Internal Medicine, New Orleans, Louisiana, USA.

出版信息

Adv Perit Dial. 1995;11:168-71.

PMID:8534696
Abstract

Only 15 cases of any etiology of Neisseria meningitidis peritonitis have been reported in the world literature since the first case in 1917. We report the first case in a continuous ambulatory peritoneal dialysis (CAPD) patient presenting with abdominal pain and cloudy peritoneal dialysis fluid. A lumbar puncture was normal. The patient died despite therapy with ceftriaxone. Autopsy confirmed this was a case of primary N. meningitidis peritonitis. Of the 15 cases of N. meningitidis reported as a cause of peritonitis, 9 patients were less than age 35 with no underlying diseases. Five cases were associated with cirrhosis or alcohol abuse. Two cases were associated with meningitis, and 1 patient was on steroid therapy for systemic lupus erythematosus. Nine of 15 patients recovered. In conclusion, N. meningitidis should be considered as another rare cause of peritonitis in patients on CAPD.

摘要

自1917年首例病例以来,世界文献中仅报道了15例由任何病因引起的脑膜炎奈瑟菌腹膜炎。我们报告了首例持续性非卧床腹膜透析(CAPD)患者出现腹痛和浑浊腹膜透析液的病例。腰椎穿刺结果正常。尽管使用头孢曲松进行了治疗,患者仍死亡。尸检证实这是一例原发性脑膜炎奈瑟菌腹膜炎病例。在报告为腹膜炎病因的15例脑膜炎奈瑟菌病例中,9例患者年龄小于35岁,无基础疾病。5例与肝硬化或酒精滥用有关。2例与脑膜炎有关,1例患者因系统性红斑狼疮接受类固醇治疗。15例患者中有9例康复。总之,脑膜炎奈瑟菌应被视为CAPD患者腹膜炎的另一种罕见病因。

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