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淀粉粉末手套对大鼠粘连形成的影响。

The impact of starch-powdered gloves on the formation of adhesions in rats.

作者信息

Holmadhl L, al-Jabreen M, Xia G, Risberg B

机构信息

Department of Surgery, Ostra Hospital, University of Göteborg, Sweden.

出版信息

Eur J Surg. 1994 May;160(5):257-61.

PMID:8075192
Abstract

OBJECTIVE

To assess the influence of starch powdered surgical gloves on the postoperative formation of adhesions in a standard rat model.

DESIGN

Prospective, randomised, double-blind study.

MATERIAL

197 rats.

INTERVENTIONS

Abdominal cavity was exposed to gloves during the induction of adhesions and for an additional two minutes. Animals were operated on with the operator wearing either starch-powdered or powder-free gloves.

MAIN OUTCOME MEASURES

Formation of adhesions and starch particles present in the adhesions after one, three, 12, or 24 weeks.

RESULTS

When powdered gloves were worn the percentage of adhesions formed was significantly greater (n = 197, p < 0.01) than when powder-free gloves were worn. Starch particles were found in biopsy specimens from rats operated on with powdered gloves, but not when powder-free gloves were used.

CONCLUSION

Even the small amount of starch that settles in the abdominal cavity during an operation increases the amount of adhesions formed.

摘要

目的

在标准大鼠模型中评估淀粉粉末手术手套对术后粘连形成的影响。

设计

前瞻性、随机、双盲研究。

材料

197只大鼠。

干预措施

在诱导粘连期间及额外两分钟内,将腹腔暴露于手套。手术时操作者佩戴淀粉粉末手套或无粉手套。

主要观察指标

1周、3周、12周或24周后粘连的形成情况以及粘连中存在的淀粉颗粒。

结果

佩戴粉末手套时形成粘连的百分比显著高于佩戴无粉手套时(n = 197,p < 0.01)。在使用粉末手套进行手术的大鼠活检标本中发现了淀粉颗粒,而使用无粉手套时未发现。

结论

即使手术期间少量沉积在腹腔内的淀粉也会增加粘连形成的数量。

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