• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

膝下截肢失败后的翻修术。使用庆大霉素胶原蛋白进行局部清创。

Revision of failed below knee amputations. Local debridement with gentamicin collagen.

作者信息

Spruit M, Bosman C H

机构信息

Department of Orthopaedic Surgery, St. Maartenskliniek Nijmegen, The Netherlands.

出版信息

Eur J Surg. 1994 May;160(5):267-70.

PMID:8075194
Abstract

OBJECTIVE

To describe our results with a new technique of revision of failed below knee amputation stumps using gentamicin impregnated collagen sponge.

DESIGN

Open study.

SETTING

District hospital.

SUBJECTS

31 patients who underwent below knee amputations between 1988 and 1992, compared with 31 historical controls who were operated on between 1984 and 1988.

INTERVENTIONS

Two thirds of the stumps that failed to heal underwent excision of necrotic and devitalised tissue; half had shortening of tibia and fibula and a gentamicin impregnated collagen sponge was left in the wound, which was then closed.

MAIN OUTCOME MEASURES

Successful wound healing and rehabilitation.

RESULTS

12 Stumps failed to heal, 8 of which were suitable for local treatment with the gentamicin sponge. All 8 healed satisfactorily, though one required revision of the scar 6 months later. Of the remainder, the stumps were converted to above knee amputations (n = 3) and one was disarticulated at the knee. In the control group 5 of the 7 stumps in which healing failed, were converted to above knee amputations and the other two healed after split skin grafting.

CONCLUSION

We think that local treatment with the collagen sponge with gentamicin offers a viable alternative to conversion to above knee amputation for below knee amputation stumps that fail to heal. The treatment should now be subjected to a randomised controlled trial.

摘要

目的

描述我们使用庆大霉素浸渍胶原海绵对失败的膝下截肢残端进行翻修的新技术的结果。

设计

开放性研究。

地点

地区医院。

研究对象

1988年至1992年间接受膝下截肢的31例患者,与1984年至1988年间接受手术的31例历史对照患者进行比较。

干预措施

三分之二愈合失败的残端进行坏死和失活组织切除;一半患者进行胫腓骨缩短术,并在伤口内留置庆大霉素浸渍胶原海绵,然后缝合伤口。

主要观察指标

伤口成功愈合及康复情况。

结果

12个残端愈合失败,其中8个适合用庆大霉素海绵进行局部治疗。所有8个均愈合良好,尽管有1个在6个月后需要对瘢痕进行翻修。其余患者中,残端改为膝上截肢(n = 3),1个在膝关节处离断。在对照组中,7个愈合失败的残端中有5个改为膝上截肢,另外2个在植皮后愈合。

结论

我们认为,对于愈合失败的膝下截肢残端,用含庆大霉素的胶原海绵进行局部治疗为改为膝上截肢提供了一种可行的替代方法。现在应对该治疗方法进行随机对照试验。

相似文献

1
Revision of failed below knee amputations. Local debridement with gentamicin collagen.膝下截肢失败后的翻修术。使用庆大霉素胶原蛋白进行局部清创。
Eur J Surg. 1994 May;160(5):267-70.
2
A prospective randomized comparison of healing in Gritti-Stokes and through-knee amputations.格里蒂-斯托克斯截肢术与经膝截肢术愈合情况的前瞻性随机对照研究。
Ann R Coll Surg Engl. 1987 Jan;69(1):1-4.
3
Level selection in leg amputation for arterial occlusive disease: a comparison of clinical evaluation and skin perfusion pressure.动脉闭塞性疾病下肢截肢的平面选择:临床评估与皮肤灌注压的比较
Acta Orthop Scand. 1982 Oct;53(5):821-31. doi: 10.3109/17453678208992300.
4
Use of tissue expansion in revision of unhealed below-knee amputation stumps.组织扩张术在未愈合的膝下截肢残端修复中的应用。
Scand J Plast Reconstr Surg Hand Surg. 2001 Jun;35(2):193-6. doi: 10.1080/028443101300165336.
5
A prospective study of lower limb amputations.
Can J Surg. 1983 Jul;26(4):339-41.
6
Muscle transposition and skin grafting for salvage of below-knee amputation level after bilateral lower extremity thermal injury.双侧下肢热损伤后,采用肌肉转位和皮肤移植术挽救膝下截肢平面。
Burns. 2001 Dec;27(8):849-52. doi: 10.1016/s0305-4179(01)00053-5.
7
Primary closure of below-knee amputation stumps: a prospective study of sixty-two cases.膝下截肢残端的一期缝合:62例前瞻性研究。
Ann Vasc Surg. 1990 Mar;4(2):143-6. doi: 10.1007/BF02001369.
8
Influence of failed vascular bypass procedures on conversion of below-knee to above-knee amputation levels.
Surgery. 1982 Jan;91(1):64-9.
9
Functional outcome after redo below-knee amputation.膝下再次截肢后的功能结局。
World J Surg. 2008 Aug;32(8):1823-6. doi: 10.1007/s00268-008-9500-5.
10
Wound healing in below-knee amputations in relation to skin perfusion pressure.
Acta Orthop Scand. 1979 Feb;50(1):49-58. doi: 10.3109/17453677909024089.