萘啶霉素，一种新型广谱抗生素。

Naphthyridinomycin, a new broad-spectrum antibiotic.

作者信息

Kluepfel D, Baker H A, Piattoni G, Sehgal S N, Sidorowicz A, Singh K, Vézina C

出版信息

J Antibiot (Tokyo). 1975 Jul;28(7):497-502. doi: 10.7164/antibiotics.28.497.

DOI:10.7164/antibiotics.28.497

Abstract

A new antibiotic, naphthyridinomycin, was isolated in crystalline form from the culture filtrate of Streptomyces lusitanus AY B-1026. The antibiotic is active against a large number of both gram-positive and gram-negative bacteria, and inactive against Candida albicans, Trichophyton granulosum and Microsporum gypseum. The antibiotic is toxic in mice.

摘要

一种新的抗生素——萘啶霉素，以结晶形式从葡萄牙链霉菌AY B - 1026的培养滤液中分离出来。该抗生素对大量革兰氏阳性菌和革兰氏阴性菌均有活性，而对白色念珠菌、颗粒状毛癣菌和石膏样小孢子菌无活性。该抗生素对小鼠有毒性。