van't Veer M B, Gratama J W
Department of Haematology, Rotterdam, The Netherlands.
Leuk Lymphoma. 1994;13 Suppl 1:77-9. doi: 10.3109/10428199409052680.
Sending material at regular intervals to laboratories that perform immunophenotyping of leukaemias and lymphomas showed a large variety in the percentage of positive cells between the different laboratories but an agreement in diagnosis of more than 90%. Each laboratory used his own methods but antibody panels and guide-lines for interpretation were standardised. Studies are in progress to answer the question if standardisation in flow cytometry will result in more comparable results.
定期向进行白血病和淋巴瘤免疫表型分析的实验室发送材料,结果显示不同实验室之间阳性细胞百分比差异很大,但诊断一致性超过90%。每个实验室都使用自己的方法,但抗体组合和解读指南是标准化的。目前正在进行研究,以回答流式细胞术标准化是否会产生更具可比性结果的问题。