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鸡肝细胞细胞核基质的糖蛋白

Glycoproteins of the nuclear matrix from chicken liver cells.

作者信息

Ferraro A, Eufemi M, Altieri F, Cervoni L, Turano C

机构信息

Dipartimento di Scienze Biochimiche, Università La Sapienza, Roma, Italia.

出版信息

Cell Biol Int. 1994 Jun;18(6):655-61. doi: 10.1006/cbir.1994.1092.

Abstract

The nuclear matrix from chicken liver cells contains a small amount of glycoproteins recognized by Concanavalin A. These proteins are present not only in the peripheral matrix, but also in the internal one. In this latter localization many glycoprotein species appear, by cross-linking experiments, to be placed in the proximity of DNA. The effect of a partial enzymatic deglycosylation of matrix preparations suggests that these proteins contribute to the stabilization of the native matrix structure.

摘要

鸡肝细胞的核基质含有少量可被伴刀豆球蛋白A识别的糖蛋白。这些蛋白质不仅存在于外周基质中,也存在于内部基质中。通过交联实验发现,在后一种定位中,许多糖蛋白种类似乎位于DNA附近。对基质制剂进行部分酶促去糖基化的作用表明,这些蛋白质有助于天然基质结构的稳定。

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