O'Neill T, Silman A J
ARC Epidemiology Research Unit, University of Manchester, UK.
Baillieres Clin Rheumatol. 1994 May;8(2):245-61. doi: 10.1016/s0950-3579(94)80017-0.
Psoriatic arthritis was first described in the early part of the nineteenth century. Over the past 50 years, concepts of the disease have evolved as a result of clinical, epidemiological, radiological and immunogenetic study. Epidemiological and clinical investigations suggest that the disease is a unique arthropathy rather than the coincident occurrence of two common diseases. There are no validated criteria for classification; this is partly because of the heterogeneous clinical features associated with the disease, and the relapsing and remitting nature of both psoriasis and arthritis. Clinical subgroups have been proposed and have proved useful in study of the disease; however, there are inconsistencies and overlaps in the published data. The population prevalence of psoriatic arthritis is in the range of 2-10 per 10,000 although this is probably an underestimate as those with sacroiliac involvement only are not included. There are currently no incidence figures from population samples. The disease is slightly more common in females than males, although there is variation in the sex ratio by disease subgroup. There is evidence that hormonal and environmental factors play a role in the occurrence of disease.
银屑病关节炎最早于19世纪初被描述。在过去的50年里，由于临床、流行病学、放射学和免疫遗传学研究，该疾病的概念不断演变。流行病学和临床调查表明，这种疾病是一种独特的关节病，而不是两种常见疾病的同时发生。目前尚无经过验证的分类标准；部分原因是与该疾病相关的临床特征具有异质性，以及银屑病和关节炎的复发和缓解特性。已经提出了临床亚组，并且已证明其在该疾病的研究中有用；然而，已发表的数据存在不一致和重叠之处。银屑病关节炎的人群患病率在每10000人中有2至10例，不过这可能是低估了，因为仅累及骶髂关节的患者未被纳入。目前尚无来自人群样本的发病率数据。该疾病在女性中比男性略为常见，尽管按疾病亚组划分的性别比例存在差异。有证据表明，激素和环境因素在该疾病的发生中起作用。
