Hanly W C, Knight K L
J Immunol. 1975 Aug;115(2):590-4.
Intestinal tissue from rabbits heterozygous at one or both of the alpha-chain subclass loci, i.e., f or g, was examined with mixtures of rhodamine-labeled and fluorescein-labeled antibodies each directed against one of the allelic products of the f or g locus. Individual plasma cells were stained by only one fluorescent reagent and thus exhibited both allelic exclusion and sublcass exclusion. In contrast, the epithelial cells of the Lieberkükhn's glands sid not exhibit allelic exclusion. Studies with rabbits heterozygous at the f and g loci revealed that the ratio of the number of cells expressing maternal-type f cells to paternal-type f is equal to the ratio of the number of maternal-type g cells to paternal-type g cells. These data are used to suggest that the expression of each of the genes in the heavy chain chromosomal region of a particular allogroup is under the same control.
对在α链亚类基因座（即f或g）一个或两个基因座上杂合的兔子的肠道组织，用分别针对f或g基因座等位基因产物之一的罗丹明标记和荧光素标记抗体混合物进行检测。单个浆细胞仅被一种荧光试剂染色，因此表现出等位基因排斥和亚类排斥。相比之下，利伯屈恩腺的上皮细胞未表现出等位基因排斥。对在f和g基因座杂合的兔子的研究表明，表达母本型f细胞的数量与父本型f细胞数量的比率，等于母本型g细胞数量与父本型g细胞数量的比率。这些数据被用来表明特定同种异型组重链染色体区域中每个基因的表达受相同的控制。
