Madore F, Wuest M, Ethier J H
Service de néphrologie, Hôtel-Dieu de Montréal, Université de Montréal, Québec, Canada.
Clin Nephrol. 1994 Jun;41(6):377-82.
Malnutrition is frequent in chronic hemodialysis patients. Standard nutritional evaluation is based on anthropometric, laboratory and clinical parameters from which a malnutrition index can be derived. Bioelectrical impedance, more rapid and practical, can be used to evaluate body composition. The goals of our study were to: 1) evaluate the incidence of and some of the factors associated with malnutrition in hemodialysis patients; 2) assess the accuracy of a scoring system based on impedance results to identify malnourished patients as defined by the malnutrition index (based on anthropometric, laboratory and clinical parameters). Standard nutritional evaluation and impedance measurements were performed on 33 chronic hemodialysis patients. Using malnutrition index, 18 patients (54%) were severely or moderately malnourished. Dietary assessment revealed a high proportion of patients with insufficient protein or calorie intake. By multiple regression analysis, the only factor significantly correlated with the malnutrition index was calorie intake (r = 0.44); age, sex, years on hemodialysis, protein intake were not. Results obtained with impedance were strongly correlated to those obtained with anthropometry for the proportion of fat mass (r = 0.72) and lean body mass (r = 0.71) and for the malnutrition index (r = 0.78). The sensitivity of the scoring system based on impedance to identify moderately or severely malnourished patients as determined by standard nutritional evaluation was 100% and its specificity was 80%. The positive and negative predictive values were respectively 85% and 100%. In summary, malnutrition is frequent and associated with low caloric intake. Bioelectrical impedance, with the use of the scoring system we describe, can be used to correctly evaluate the nutritional status of hemodialysis patients.
营养不良在慢性血液透析患者中很常见。标准营养评估基于人体测量学、实验室和临床参数,从中可以得出营养不良指数。生物电阻抗测量更快速、实用,可用于评估身体成分。我们研究的目的是:1)评估血液透析患者营养不良的发生率及一些相关因素;2)评估基于阻抗结果的评分系统识别由营养不良指数(基于人体测量学、实验室和临床参数)定义的营养不良患者的准确性。对33例慢性血液透析患者进行了标准营养评估和阻抗测量。使用营养不良指数,18例患者(54%)存在重度或中度营养不良。饮食评估显示,蛋白质或热量摄入不足的患者比例很高。通过多元回归分析,与营养不良指数显著相关的唯一因素是热量摄入(r = 0.44);年龄、性别、血液透析年限、蛋白质摄入量则无相关性。阻抗测量结果与人体测量学结果在脂肪量比例(r = 0.72)、瘦体重比例(r = 0.