关于阿米巴病的一些免疫学研究。
Some immunological studies on amoebiasis.
作者信息
el-Ganayni G A, Attia R A, el-Naggar H M
机构信息
Department of Parasitology, Faculty of Medicine, Mansoura University, Egypt.
出版信息
J Egypt Soc Parasitol. 1994 Aug;24(2):357-62.
Studies of immunoglobulins pattern in 64 patients with different clinical symptoms of amoebiasis revealed that IgG showed no rise in patients with acute amoebic dysentery and asymptomatic cyst passers, while it was significantly increased in patients with active hepatic amoebiasis. IgM, IgA and IgE were significantly increased in both acute amoebic dysentery and active hepatic amoebiasis, but no significant changes in asymptomatic cyst passers. ELISA (depended on level of IgG) was valid and reliable in diagnosis of active hepatic amoebiasis (100%), IHAT (depended on level of IgM) gave 72.7% and 46.9% in patients with acute amoebic dysentery and active hepatic amoebiasis respectively.
对64例有不同阿米巴病临床症状患者的免疫球蛋白模式研究显示，急性阿米巴痢疾患者和无症状排包囊者的IgG未升高，而活动性肝阿米巴病患者的IgG显著升高。急性阿米巴痢疾和活动性肝阿米巴病患者的IgM、IgA和IgE均显著升高，但无症状排包囊者无显著变化。ELISA（取决于IgG水平）在诊断活动性肝阿米巴病方面有效且可靠（100%），间接血凝试验（取决于IgM水平）在急性阿米巴痢疾患者和活动性肝阿米巴病患者中的阳性率分别为72.7%和46.9%。
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