Jess P
Department of Surgical Gastroenterology, Herlev Hospital, University of Copenhagen, Denmark.
J Intern Med. 1994 Sep;236(3):271-4. doi: 10.1111/j.1365-2796.1994.tb00795.x.
To investigate the direction of a possible relationship between peptic ulcer disease and personality disorders.
A cohort study of 50-year old patients, observed for 2 decades.
Glostrup County, Denmark (population 100000).
A representative sample of 50-year old people born in 1914 (n = 673) were followed for 20 years. All 673 filled in the Minnesota Multiphasic Personality Inventory (MMPI) in 1964 and 513 were retested with MMPI in 1974.
Prevalence of peptic ulcer disease 1964, incidence of peptic ulcer disease 1964-84, MMPI scores.
The prevalence of peptic ulcer disease in 1964 was 7% and the average annual incidence in the period 1964-84 was 2.1 per 1000 persons. Those with incidental peptic ulcer in 1964-84 had normal MMPI scores in 1964, whilst those with peptic ulcer in 1964 had a slight but statistically significant increase in one neuroticism scale (HS) only. The group with prevalent ulcer disease in 1974 exhibited statistically significant increases in the three neuroticism scales (HS, D, HY) and in scale Pd and scale Pt at MMPI retesting. In addition they had statistically significantly higher scores in the three neuroticism scales compared with the other persons who still had normal scores in all scales.
Personality disorders in patients with peptic ulcer are consequences of the disease and not causal factors.
研究消化性溃疡疾病与人格障碍之间可能存在的关系方向。
对50岁患者进行队列研究，观察20年。
丹麦格罗斯特鲁普县（人口100000）。
对1914年出生的50岁人群的代表性样本（n = 673）进行了20年的随访。所有673人在1964年填写了明尼苏达多相人格调查表（MMPI），1974年对其中513人进行了MMPI复测。
1964年消化性溃疡疾病的患病率、1964 - 1984年消化性溃疡疾病的发病率、MMPI分数。
1964年消化性溃疡疾病的患病率为7%，1964 - 1984年期间的年平均发病率为每1000人2.1例。1964 - 1984年偶发性消化性溃疡患者在1964年的MMPI分数正常，而1964年患有消化性溃疡的患者仅在一个神经质量表（HS）上有轻微但具有统计学意义的升高。1974年患有现患溃疡疾病的组在MMPI复测时，三个神经质量表（HS、D、HY）以及量表Pd和量表Pt均有统计学意义的升高。此外，与所有量表分数仍正常的其他人相比，他们在三个神经质量表上的分数在统计学上显著更高。
消化性溃疡患者的人格障碍是疾病的后果而非病因。
