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口服α-硫辛酸治疗糖尿病性神经病变(作者译)

[Treatment of diabetic neuropathy with oral alpha-lipoic acid (author's transl)].

作者信息

Klein W

出版信息

MMW Munch Med Wochenschr. 1975 May 30;117(22):957-8.

PMID:807811
Abstract

100 patients were treated with Thioctacid orally for diabetic neuropathy. A successful assessment was possible with sufficient certainty in 89 patients. Of these, 29 received 2 X 50 mg and 60 patients 2 X 100 mg Thioctacid daily. In the first group the treatment was successful in 23 patients, and in 51 of the second group. According to these findings, administration of thiotic acid is effective in diabetic neuropathy just as frequently orally as intravenously.

摘要

100名糖尿病性神经病变患者口服硫辛酸进行治疗。89名患者能够得到足够确定的成功评估。其中,29名患者每日服用2次,每次50毫克硫辛酸,60名患者每日服用2次,每次100毫克硫辛酸。第一组中有23名患者治疗成功,第二组中有51名患者治疗成功。根据这些发现,硫辛酸治疗糖尿病性神经病变时,口服与静脉注射的疗效同样显著。

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