Kolokotronis A, Kioses V, Antoniades D, Mandraveli K, Doutsos I, Papanayotou P
School of Dentistry, Aristotle University of Thessaloniki, Specific Infectious Diseases Unit, Greece.
Oral Surg Oral Med Oral Pathol. 1994 Jul;78(1):36-40. doi: 10.1016/0030-4220(94)90114-7.
A follow-up study included the oral examination of 39 persons known to be infected with the human immunodeficiency virus. In addition to the other human immunodeficiency virus-associated oral lesions, lesions clinically similar to the smooth form of median rhomboid glossitis, which is now believed to be erythematous candidiasis located in the dorsum of the tongue, were found in seven patients (18%). Patients with median rhomboid glossitis were classified in different stages of the Centers for Disease Control 1986 classification system and showed an average of CD+4 cell counts 397.5/mm3. Also the presence or the absence of anti-p24 antibodies in the serum and stimulated whole saliva of the patients with median rhomboid glossitis did not correlate with the stage of the disease or with low levels of CD+4 cell counts as in other forms of oral candidiasis. Therefore our results suggest that median rhomboid glossitis should be included as a distinct form of oral candidiasis in the classification of the oral manifestations of infection with the human immunodeficiency virus.
一项随访研究对39名已知感染人类免疫缺陷病毒的人员进行了口腔检查。除了其他与人类免疫缺陷病毒相关的口腔损害外，在7名患者（18%）中发现了临床上类似于正中菱形舌炎光滑型的损害，目前认为该损害是位于舌背的红斑型念珠菌病。正中菱形舌炎患者按照疾病控制中心1986年分类系统分为不同阶段，其CD +4细胞计数平均为397.5/mm³。此外，正中菱形舌炎患者血清和刺激全唾液中抗p24抗体的有无与疾病阶段或与其他形式口腔念珠菌病中CD +4细胞计数低水平均无相关性。因此，我们的结果表明，在人类免疫缺陷病毒感染口腔表现的分类中，正中菱形舌炎应作为一种独特的口腔念珠菌病形式纳入其中。
