Gururangan S, Wilimas J A, Fletcher B D
Department of Hematology-Oncology, St. Jude Children's Research Hospital, Memphis, Tennessee.
Pediatr Radiol. 1994;24(2):85-7. doi: 10.1007/BF02020158.
Bone metastases are extremely rare in patients with classical Wilms' tumor (WT). We describe the clinical and radiologic features, treatment and outcome of three patients with WT (one with favorable histology and two with anaplasia) in whom bone metastases were detected at diagnosis or relapse. Bone metastases were documented by skeletal radiographs, computed tomography and/or bone scintigraphy. The patient with favorable histology WT had no evidence of pulmonary metastases and is now free of disease following aggressive chemotherapy and radiotherapy.
骨转移在经典型肾母细胞瘤(WT)患者中极为罕见。我们描述了3例WT患者(1例组织学类型良好,2例为间变)在诊断或复发时检测到骨转移的临床和放射学特征、治疗及转归。通过骨骼X线片、计算机断层扫描和/或骨闪烁显像记录骨转移情况。组织学类型良好的WT患者无肺转移证据,在接受积极的化疗和放疗后目前已无疾病。