Marsden H B, Lennox E L, Lawler W, Kinnier-Wilson L M
Br J Cancer. 1980 Jun;41(6):875-9. doi: 10.1038/bjc.1980.163.
Analysis of data from 1434 children with primary renal tumours revealed 57 who developed bone metastases. Of these, 54 were initially recorded as nephroblastoma. Fifty-two of the 57 cases were reviewed histologically, and only 18 were found to be Wilms' tumours. Twenty-three were classified as "Bone-Metastasizing Renal Tumour of Childhood" (BMRTC), and a high male incidence was found for these tumours (M:F=6.7:1). Differences in the pattern of metastasis and the one-year survival between BMRTC and nephroblastoma are discussed. The rarity of bone metastases from true Wilms' tumours is emphasized.
对1434例原发性肾肿瘤患儿的数据进行分析后发现，有57例发生了骨转移。其中，54例最初被记录为肾母细胞瘤。57例中的52例进行了组织学复查，结果仅发现18例为威尔姆斯瘤。23例被归类为“儿童骨转移性肾肿瘤”（BMRTC），这些肿瘤男性发病率较高（男:女 = 6.7:1）。文中讨论了BMRTC与肾母细胞瘤在转移模式和一年生存率方面的差异。强调了真正的威尔姆斯瘤发生骨转移的罕见性。
