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[儿科急诊室呼吸道感染的抗生素治疗]

[The antibiotic treatment of respiratory infections in a pediatric emergency room].

作者信息

Marchi A G, Canciani M

机构信息

Servizio di Pronto Soccorso e Primo Accogliamento, Istituto per l'Infanzia, Burlo Garofolo di Trieste, Italia.

出版信息

Pediatr Med Chir. 1994 Mar-Apr;16(2):141-3.

PMID:8078788
Abstract

Eight years after the first study published in this Journal (1985, 7: 533), we compared antibiotic treatment of respiratory infections at the Pediatric Emergency Department of the Children's Hospital in Trieste. All patients with pneumonia and pertussis received antibiotics, compared to 87% of otitis, 55% of pharyngo-tonsillitis, 4% of upper respiratory infections (U.R.I.); neither asthma nor laryngitis were treated with antibiotics. In particular, only 13% of otitis were treated by symptomatics, the others with amoxicillin (51%), amoxicillin + clavulanic acid (18%), cefaclor (12%), trimethoprim-sulphamethoxazole (5%), josamycin (1%). 45% of pharyngo-tonsillitis was treated with symptomatics, 32% with macrolides and 10% with penicillin; rarer treatment comprehended amoxicillin, amoxicillin + clavulanic acid (10%) and cefaclor (3%). Pneumonia was treated with amoxicillin or cefaclor (30% both), with amoxicillin + clavulanic acid (10%) or with macrolides (30%), the last in provision of mycoplasmal etiology. Antibiotic treatment of U.R.I. is progressively decreased from 79% in 1974 to 13% in 1983 and to 4% in 1991. Antibiotic treatment in our Department was appropriate in the majority of patients, with almost all bacterial form treated with first choice, cheaper antibiotic. A negative, limited trend was detected for pharyngo-tonsillitis: first choice antibiotics passed from 82% in 1983 to 76% in 1991. Another positive factor is due to the homogeneous manners of the doctors working at the Emergency Department, belonging to two different teams (Emergency and Clinical Departments), probably with the use of common clinical protocols.(ABSTRACT TRUNCATED AT 250 WORDS)

摘要

在本杂志发表首项研究(1985年,第7卷,第533页)的八年后,我们对的里雅斯特儿童医院儿科急诊科呼吸道感染的抗生素治疗情况进行了比较。所有肺炎和百日咳患者均接受了抗生素治疗,相比之下,中耳炎患者接受抗生素治疗的比例为87%,咽扁桃体炎患者为55%,上呼吸道感染(U.R.I.)患者为4%;哮喘和喉炎患者均未使用抗生素治疗。具体而言,只有13%的中耳炎患者接受对症治疗,其他患者使用阿莫西林治疗的比例为51%,阿莫西林+克拉维酸治疗的比例为18%,头孢克洛治疗的比例为12%,甲氧苄啶-磺胺甲恶唑治疗的比例为5%,交沙霉素治疗的比例为1%。45%的咽扁桃体炎患者接受对症治疗,32%的患者使用大环内酯类药物治疗,10%的患者使用青霉素治疗;较少见的治疗方式包括使用阿莫西林、阿莫西林+克拉维酸(10%)和头孢克洛(3%)。肺炎患者使用阿莫西林或头孢克洛治疗的比例均为30%,使用阿莫西林+克拉维酸治疗的比例为10%,或使用大环内酯类药物治疗的比例为30%,最后一种用于支原体病因的情况。上呼吸道感染的抗生素治疗比例从1974年的79%逐渐降至1983年的13%,并在1991年降至4%。我们科室的抗生素治疗在大多数患者中是恰当的,几乎所有细菌感染形式都使用了首选的、更便宜的抗生素。在咽扁桃体炎方面检测到一个负面的、有限的趋势:首选抗生素的比例从1983年的82%降至1991年的76%。另一个积极因素是,在急诊科工作的医生,分属两个不同团队(急诊科和临床科室),工作方式较为一致,这可能是由于使用了共同的临床方案。(摘要截选至250词)

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