Pustorino S, Federico G, Calipari G, Martinez P, Pizzimenti C, Barbera G, Salvia M A, Migliorato D, Consolo F
Cattedra di Gastroenterologia, Università, Messina.
Recenti Prog Med. 1994 Jul-Aug;85(7-8):362-7.
Low-compliance standard manometry and 24-hour ambulatory pH monitoring were performed in 42 patients with typical gastro-esophageal reflux (GER) symptoms in order to assess correlations between esophageal motility pattern and pH profile. Our results show: 1) 36% of GER patients had a normal esophageal acid exposure; 2) pH profile and manometric pattern did not differ in patients with mild esophagitis from those without esophagitis; 3) low esophageal sphincter pressure in GER patients was significantly lower than in control subjects, irrespective of acid exposure; 4) the main motility disorders in the distal esophagus of reflux patients was the increased simultaneous wave rate which seemed to affect both recumbent esophageal clearance and reflux time.
对42例有典型胃食管反流(GER)症状的患者进行了低顺应性标准测压和24小时动态pH监测,以评估食管动力模式与pH曲线之间的相关性。我们的结果显示:1)36%的GER患者食管酸暴露正常;2)轻度食管炎患者与无食管炎患者的pH曲线和测压模式无差异;3)无论酸暴露情况如何,GER患者的食管下括约肌压力均显著低于对照组;4)反流患者远端食管的主要动力障碍是同步波发生率增加,这似乎影响了卧位时食管清除率和反流时间。