犬心肺复苏期间动脉血与静脉血二氧化碳分压差值及心输出量情况

Arteriovenous differences in PCO2 and cardiac output during CPR in the dog.

作者信息

Sato S, Okubo N, Satsumae T, Kumagai M, Yamamoto S, Nakayama H, Taguchi N

机构信息

Department of Anesthesiology, University of Tsukuba, Ibaraki, Japan.

出版信息

Resuscitation. 1994 May;27(3):255-9. doi: 10.1016/0300-9572(94)90039-6.

DOI:10.1016/0300-9572(94)90039-6

PMID:8079059

Abstract

Using 14 mongrel dogs, we investigated the correlation between arteriovenous differences of PCO2 (AVD-CO2) and cardiac output (CO) during CPR. Ventricular fibrillation was induced by an electrical current and the respirator was stopped for 5 min. Cardiopulmonary resuscitation (CPR) was performed during the next 10 min and CO was measured with simultaneous arterial and venous blood gas analysis. CO was measured 26 times during CPR. The animals were divided into two groups according to the values of CO during CPR: low-CO group (CO < 0.3 l/min) and high-CO group (CO > or = 0.3 l/min). AVD-CO2 in the low CO group was 39.8 +/- 5.7 mmHg and that of the high group was 27.4 +/- 14.8 mmHg (mean +/- S.D., P < 0.05). In conclusion, AVD-CO2 showed an inverse result with the degree of CO during CPR.

摘要

我们使用14只杂种狗，研究了心肺复苏期间动脉血与静脉血二氧化碳分压差（AVD-CO2）与心输出量（CO）之间的相关性。通过电流诱发心室颤动，并停止呼吸5分钟。在接下来的10分钟内进行心肺复苏（CPR），并通过同步动脉和静脉血气分析测量心输出量。在心肺复苏期间测量心输出量26次。根据心肺复苏期间的心输出量值将动物分为两组：低心输出量组（CO<0.3升/分钟）和高心输出量组（CO≥0.3升/分钟）。低心输出量组的AVD-CO2为39.8±5.7 mmHg，高心输出量组为27.4±14.8 mmHg（平均值±标准差，P<0.05）。总之，心肺复苏期间AVD-CO2与心输出量程度呈相反结果。