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[Allergic angiitis with granulomatosis: the Churg and Strauss syndrome].

作者信息

Lhote F, Guillevin L, Godeau P

机构信息

Service de médecine interne, hôpital Delafontaine, Saint-Denis, France.

出版信息

Rev Med Interne. 1994;15 Suppl 2:226s-233s. doi: 10.1016/s0248-8663(05)82240-4.

Abstract

Churg-Strauss Syndrome is a disorder characterized by pulmonary and systemic necrotizing vasculitis, extravascular granulomas, and eosinophilia occurring almost exclusively in patients with asthma or a history of allergy. The clinical manifestations most commonly associated with asthma are mononeuritis multiplex, gastrointestinal, cutaneous, cardiac and renal involvement. ANCA are found in 2/3 of the patients with Churg-Strauss Syndrome and are usually p-ANCA. The treatment of Churg-Strauss Syndrome relies on corticosteroids and cyclophosphamide.

摘要

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