Perepanova T S, Darenkov A F, Kagan E V, Kotliarova G A, Kondrat'eva E M, Lavrinova L N, Grishkova N V, Siniukhin V N
Urol Nefrol (Mosk). 1994 May-Jun(3):14-7.
A clinical trial was made of a new gel ligenten intended for local urethral anesthesia and treatment of infection and inflammation in the lower urinary tracts. Ligenten was given to 52 patients to manage bladder, prostate, urethral infection and inflammation, for local prophylaxis before cystoscopy, urethral bouginage and transurethral surgery. Apparent advantages of intraurethral introduction of the analgetic compared to instrument lubrication are demonstrated. Ligenten was also effective against chronic cystitis, cystalgia and urethral syndrome in females, especially in ulcerative cystitis. The gel exhibited adequate antiinflammatory and analgetic effect. As a prophylactic means, it prevents inflammation in cystoscopy, urethral catheterization and transurethral operations. No severe side effects have been reported.
对一种用于局部尿道麻醉以及治疗下尿路感染和炎症的新型凝胶利根汀进行了一项临床试验。52例患者使用利根汀来治疗膀胱、前列腺、尿道感染和炎症，以及在膀胱镜检查、尿道探条扩张术和经尿道手术前进行局部预防。结果表明，与器械润滑相比，尿道内注入该镇痛药具有明显优势。利根汀对女性慢性膀胱炎、膀胱疼痛和尿道综合征也有效，尤其是对溃疡性膀胱炎。该凝胶显示出足够的抗炎和镇痛效果。作为一种预防手段，它可防止膀胱镜检查、尿道插管和经尿道手术中的炎症。未报告有严重副作用。
