Perepanova T S, Darenkov A F, Kagan E Z, Pozdniakova V P, Sinitsina N I, Kotliarova T S, Kondrat'eva E M, Lavrinova L N, Grishkova N V, Siniukhin V N
Antibiot Khimioter. 1993 Dec;38(12):35-8.
A new therapeutic in the form of a gel named ligenten was studied. The gel active components are lidocain, gentamicin and ethonium. Ligenten was shown to have a marked local anesthetic action when administered transurethrally. As a prophylactic agent the gel was highly active against the majority of the causative agents of renal infections due to cystoscopy, catheterization and bougienage of the urethra. Ligenten provided a sufficient anesthetic effect in transurethral operations but did not prevent superinfection due to the hospital strains. Marked antiinflammatory and reparative actions of the gel especially in the treatment of ulcerous cystitis were observed.
对一种名为利根廷(ligenten)的凝胶形式的新型疗法进行了研究。该凝胶的活性成分是利多卡因、庆大霉素和乙磺铵。经尿道给药时,利根廷显示出显著的局部麻醉作用。作为一种预防剂,该凝胶对因膀胱镜检查、导尿和尿道扩张术引起的大多数肾脏感染病原体具有高度活性。利根廷在经尿道手术中提供了足够的麻醉效果,但不能预防医院菌株引起的二重感染。观察到该凝胶具有显著的抗炎和修复作用,尤其是在治疗溃疡性膀胱炎方面。