McDonald D J
Department of Orthopedic Surgery, Saint Louis University Health Sciences Center, St. Louis, MO 63110.
AJR Am J Roentgenol. 1994 Sep;163(3):509-13; discussion 514-6. doi: 10.2214/ajr.163.3.8079835.
The management of patients with sarcomas of the appendicular skeleton with limb-sparing surgery has become the standard of care. This is the result of advances in the understanding of the biology and staging of tumors, improvement in reconstructive techniques, and development of effective adjuvant chemotherapy and radiotherapy. A limb-sparing approach is applicable to virtually any bone lesion, whether low grade or high grade, and to all of the common primary soft-tissue sarcomas.
采用保肢手术治疗四肢骨骼肉瘤患者已成为标准治疗方案。这是由于对肿瘤生物学和分期的认识取得进展、重建技术得到改进以及有效的辅助化疗和放疗得以发展。保肢方法几乎适用于任何骨病变，无论其分级为低级别还是高级别，也适用于所有常见的原发性软组织肉瘤。
