Brown D N, Rosenholtz M J, Marshall J B
Division of Gastroenterology, University of Missouri School of Medicine, Columbia.
Am J Gastroenterol. 1994 Sep;89(9):1558-61.
It is well recognized that cocaine use can be associated with serious cardiovascular complications, including myocardial infarction. Several case reports have recently linked the use of cocaine with ischemic events of the small bowel and colon. We report a case of ischemic colitis complicated by perforation in a 47-yr-old diabetic man which occurred after recreational cocaine use. The older age of the patient and underlying diabetes mellitus were unique aspects of our case, compared with others reported in the literature. The patient's history of cocaine use was not initially identified. After we obtained a negative arteriogram result, we went back to the patient and the information was revealed. The literature regarding intestinal ischemia related to cocaine and other drugs/medications is reviewed. The abuse of cocaine should be considered in the differential diagnosis of acute intestinal vascular insufficiency syndromes.
众所周知，使用可卡因可伴有严重的心血管并发症，包括心肌梗死。最近有几例病例报告将可卡因的使用与小肠和结肠的缺血性事件联系起来。我们报告一例47岁糖尿病男性在使用娱乐性可卡因后发生缺血性结肠炎并穿孔的病例。与文献中报道的其他病例相比，患者年龄较大及潜在的糖尿病是我们这个病例的独特之处。患者使用可卡因的病史最初未被发现。在我们得到血管造影结果为阴性后，我们再次询问患者，这一信息才被披露。本文对与可卡因及其他药物相关的肠道缺血的文献进行了综述。在急性肠道血管功能不全综合征的鉴别诊断中应考虑可卡因滥用。
