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吉兰-巴雷综合征与贲门失弛缓症:一种病毒性疾病的两种表现还是巧合性关联?

Guillain-Barre syndrome and achalasia: two manifestations of a viral disease or coincidental association?

作者信息

Firouzi M, Keshavarzian A

机构信息

Department of Medicine, Loyola University Medical Center, Maywood, Illinois.

出版信息

Am J Gastroenterol. 1994 Sep;89(9):1585-7.

PMID:8079948
Abstract

Guillain-Barre' syndrome and achalasia are rare diseases of uncertain cause. However, viral etiologies have been postulated for each disorder. The concomitant presence of both disorders in a patient suggests a common etiology, because a coincidental association would be exceedingly rare. Indeed, to our knowledge, the concomitant appearance of Guillain-Barre' syndrome and achalasia has not been previously reported. We now report our observation of a patient who developed dysphagia shortly after onset of Guillain-Barre' syndrome. Achalasia was subsequently diagnosed by manometry and was successfully treated by pneumatic dilation. The concomitant appearance of Guillain-Barre' syndrome and achalasia in our patient supports the notion of a viral etiology for achalasia.

摘要

格林-巴利综合征和贲门失弛缓症是病因不明的罕见疾病。然而,每种疾病都曾被推测有病毒病因。一名患者同时患有这两种疾病提示存在共同病因,因为二者巧合并存极为罕见。事实上,据我们所知,此前尚未有格林-巴利综合征和贲门失弛缓症同时出现的报道。我们现报告一例患者,其在格林-巴利综合征发病后不久出现吞咽困难。随后通过测压法诊断为贲门失弛缓症,并经气囊扩张成功治愈。我们这位患者中格林-巴利综合征和贲门失弛缓症的同时出现支持了贲门失弛缓症病毒病因的观点。

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