Oyama S, Nakajima T, Ota K, Ishihara S, Wakabayashi K, Nishi M
Division of Surgery, Cancer Institute Hospital.
Gan To Kagaku Ryoho. 1994 Aug;21(11):1762-7.
From 1946 to 1990, 10,485 patients with gastric cancer were been surgically treated in the Cancer Institute Hospital, Tokyo. Retrospectively, we analyzed prognostic factors, especially in those without distant metastasis. Prognosis of the patients with tumors which invaded the proper muscle layer improved dramatically (from 70% to 90%). However, patients who had advanced tumors with serosal invasion did not show good survived (from 20% to 40%). To improve the prognosis of patients with serosal positive gastric cancer, a new and effective prophylactic therapy for peritoneal recurrence is needed.
1946年至1990年期间，东京癌症研究所医院对10485例胃癌患者进行了手术治疗。我们进行了回顾性分析，以探讨预后因素，特别是在无远处转移的患者中。肿瘤侵犯固有肌层的患者预后显著改善（从70%提高到90%）。然而，肿瘤侵犯浆膜层的进展期患者生存率不佳（从20%到40%）。为改善浆膜阳性胃癌患者的预后，需要一种新的、有效的预防腹膜复发的治疗方法。
