De Silva H J, Ellawala N S
Department of Medicine, Faculty of Medicine, University of Kelaniya, Ragama, Sri Lanka.
Alcohol Alcohol. 1994 Mar;29(2):199-201.
The influence of temperance on short-term mortality was assessed in a group of alcohol-dependent men admitted to a rehabilitation unit in Sri Lanka. Of the 234 men initially admitted to the programme, 188 were followed up for at least 3 years (mean +/- SD 49.5 +/- 12.6 months) or until death. All 188 were totally abstinent from alcohol on leaving the 6 week residential module of the programme. During follow-up, 115 relapsed to continued heavy drinking, whereas 73 remained either totally abstinent or drank infrequently. There were no significant differences in the age, duration of dependence, number of previous interventions, duration of follow-up or smoking habits between the two groups of patients. The overall mortality for the whole sample population was 9.6%. The mortality among those who relapsed to heavy drinking (13.9%) was more than five times that of those who were abstinent or drank infrequently (2.7%) (P < 0.04). Fifteen of the 16 deaths (93.8%) among those who relapsed to heavy drinking were alcohol-related, and included five suicides and accidents whilst under the influence of alcohol. Temperance significantly reduces short-term mortality in alcohol-dependent men when compared to those who relapse to continued heavy drinking. This difference was primarily due to reduction in the risk of alcohol-related deaths.
在斯里兰卡一家康复机构收治的一组酒精依赖男性中,评估了戒酒对短期死亡率的影响。最初纳入该项目的234名男性中,188人接受了至少3年的随访(平均±标准差49.5±12.6个月)或直至死亡。所有188人在完成该项目为期6周的住院治疗模块后均完全戒酒。随访期间,115人复发并继续大量饮酒,而73人保持完全戒酒或偶尔饮酒。两组患者在年龄、依赖持续时间、既往干预次数、随访时间或吸烟习惯方面无显著差异。整个样本人群的总死亡率为9.6%。复发大量饮酒者的死亡率(13.9%)是戒酒或偶尔饮酒者(2.7%)的五倍多(P<0.04)。复发大量饮酒者中的16例死亡中有15例(93.8%)与酒精有关,包括5例自杀和酒精影响下发生的事故。与复发并继续大量饮酒者相比,戒酒显著降低了酒精依赖男性的短期死亡率。这种差异主要是由于与酒精相关的死亡风险降低。