Kristensen O, Andersen H H, Jensen J B
Acta Med Scand. 1975 Jun;197(6):463-5. doi: 10.1111/j.0954-6820.1975.tb04952.x.
Four cases of lactic acidosis in phenformintreated diabetics are presented. Blood lactate before treatment was 5.7, 9.4, 10.7 and 17.8 mM/1, respectively. Treatment with glucose, insulin and bicarbonate resulted in correction of acidosis and hyperlactataemia. This therapy is recommended in phenformin-induced lactic acidosis.
本文报告了4例服用苯乙双胍的糖尿病患者发生乳酸酸中毒的病例。治疗前血乳酸水平分别为5.7、9.4、10.7和17.8 mM/1。给予葡萄糖、胰岛素和碳酸氢盐治疗后酸中毒和高乳酸血症得到纠正。对于苯乙双胍所致乳酸酸中毒,推荐采用这种治疗方法。