促甲状腺激素释放激素的临床应用。
Clinical uses of thyrotropin-releasing hormone.
作者信息
Ramey J N, Burrow G N
出版信息
Am Fam Physician. 1975 Jul;12(1):93-100.
Knowledge about the physiology of the endocrine glands has been expanded in the past several years. It now appears that the secretion of the various pituitary hormones is conditioned by specific releasing hormones secreted in the hypothalamus. Thyrotropin-releasing hormone conditions the pituitary to release thyroid-stimulating hormone when the serum thyroid hormone concentration falls below a certain level. A radioimmunoassay for TSH helps the physician to distinguish the different etiologies of hypothyroidism, to confirm the diagnosis of "euthyroid" Graves' disease and to evaluate pituitary function.
在过去几年中，有关内分泌腺生理学的知识得到了扩展。现在看来，各种垂体激素的分泌受下丘脑分泌的特定释放激素调节。当血清甲状腺激素浓度降至某一水平以下时，促甲状腺激素释放激素促使垂体释放促甲状腺激素。促甲状腺激素的放射免疫测定有助于医生区分甲状腺功能减退的不同病因，确诊“甲状腺功能正常”的格雷夫斯病，并评估垂体功能。
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